Dr. Mitchell Weiss was a radiologist at Morton Plant Hospital and his wife, Dr. Leslie Weiss, worked as a pediatrician. Their two children 19-year-old Hannah Weiss and 16-year-old Ari Weiss were also killed.
Hannah's friends said she loved exploring the world's beauty and saw the best in everyone.
"I'm still in shock. I want to pick up the phone and call her," said family friend Ezra Bobo.
The Dean at Columbia University sent a memo to students saying:
"It is with deep sadness that I write to share with you the passing of Hannah Weiss, a second year student in the undergraduate Joint Program between Columbia University School of General Studies and List College at the Jewish Theological Seminary."
Hannah studied sustainable development and Jewish ethics in the program.
"The biggest tragedy, she didn't get to live to realize that dream on the scale that she wanted. I hope that we can help that legacy live on," said friend AJ Yablonsky.
The family was active at Congregation B'nai Israel of St. Petersburg. Dean Hershkowitz said, "this family was so bright and kind and will be missed by so many."
Details on funeral or memorial arrangements have not been announced.
Friends of Hannah said they hope everyone starts the new year by cherishing those around them.
"You never know how much time you're going to have with somebody and to treasure every moment," said Bobo.